Highlighted EBiSC Gene-edited Collections
The EBiSC Catalogue is a collection of high quality,
human iPS cells available for distribution to academic
and commercial researchers worldwide for use in disease
modelling and other forms of pre-clinical research.
Cell lines in the current EBiSC catalogue have been
made and deposited by EBiSC partner labs and a number of
external research organisations. The collection includes
isogenic cell line collections which have been genetically
modified to repair or insert disease related genotypes,
add reporter genes or include inducible transgenes to
modulate cell identity.
Can’t find the line you need? Check the
EBiSC cell line catalogue
and search by disease and affected gene
for further lines. See more information
here
and contact
EBiSC to discuss custom gene editing requests.
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APOE
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Cohorts of isogenic ApoE-ε2/ε2, ε3/ε3, ε3/ε4, ε4/ε4 and knockout iPSC lines derived from Alzheimer’s disease affected and unaffected, male and female donors.
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TREM2 and CD33
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Insertion of TREM2, CD33 disease associated genotypes into healthy control lines.
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Inducible NEUROG2
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Doxycycline controllable expression of Neurogenin2 (NEUROG2) to enable fast and effective differentiation to mature, functionally active neurons.
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SNCA
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Alpha-synuclein (SNCA) triplication line (4 alleles) with corrected isogenic controls.
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Frontotemporal Dementia
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Insertion of MAPT disease associated genotypes into healthy control lines.
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