Cell Line Collection: SNCA

IPSCs carrying an alpha-synuclein (SNCA) triplication line (4 alleles) shows a two-fold higher concentration of intracellular α-synuclein in differentiated neural cells. To support research into the role of SNCA in the development of Parkinson’s disease, isogenic and familial control lines as well as inducible SNCA lines are available. PMID: 21863007, PMID: 21863007