Project documentation

To get an overview of EBiSC, please have a look at our Infographic!

Publications

• "Development and implementation of large-scale quality control for the European bank for induced Pluripotent Stem Cells" (Stem Cell Research, March 2020)
• "Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience" (Stem Cell Research, March 2017)
• "Hot Start to European Pluripotent Stem Cell Banking" (Trends in Biotechnology, July 2017, Vol. 37 / No. 7)
• "Stem cell bio bank could lead to new drugs" (EBiSC as one of the EC Success Story, September 2017)
• EBiSC brochure presenting the EBiSC bank and iPSC catalogue (October 2017, prepared by ECACC)
• EBiSC mentioned in an article in NATURE ("M. Scudellari: A decade of iPS cells" (p. 312), June 2016)
• EBiSC related publication: "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" (Stem Cell Research, 04/01/2019)
• 🔗 EBiSC best practice: How to ensure optimal generation, qualification, and distribution of iPSC lines
• 🔗 Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line"
• 🔗 Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus
• 🔗 Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies
• 🔗 The EBiSC iPSC bank for disease studies
• 🔗 Access to stem cell data and registration of pluripotent cell lines: The Human Pluripotent Stem Cell Registry (hPSCreg)
• 🔗 Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies
• 🔗 Scalable expansion of iPSC and their derivatives across multiple lineages
• 🔗 Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease
• 🔗 SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System

EBiSC Project Reports - Executive Summaries

• Period 4 (January - December 2017) - Final Report
• Period 3 (January - December 2016)
• Period 2 (January - December 2015)
• Period 1 (January - December 2014)

Press Releases

• 2020, February: Press release to announce CHDI HD cell lines
• 2019, March: Press release to announce EBiSC2 launch
• 2016, March: Press release to announce EBiSC launch of new European Stem Cell Bank (English version)
• 2014, February: Press release to announce EBiSC project start (English version)
• 2014, February: Press release to announce EBiSC project start (German version)

Information for Potential Users

• EBiSC Protocol for the Use of iPSC Lines
• EBiSC Guidance: How to Use the Catalogue Search Interface
• EBiSC Information Sheet: Genomic Data Processing for Catalogue Search
• EBiSC Brochure
• EBiSC Protocol for using NEUR1.

Information for Potential Depositors

• EBiSC Guidance for Depositors
• Depositor Initial Application Form
• EBiSC Depositor Flyer
• EBiSC Cell Line Data Registration Guide
• EBiSC Mandatory Fields for Cell Line Registration
• EBiSC Guidance: Genetic / Genomic Data Deposition and Access
• EBiSC Consent Template
• EBiSC Participant Information Template