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STBCi025-B

SFC834-03-03

iPSC line

Stock not immediately available - enquire for details
We are currently making some changes to how EBiSC operates and because of this there is a short period of time where orders cannot be placed.

If you are interested in accessing these cells, please contact EBiSC directly. For more information about the current transition process see here.
A CLIP contains information about a cell line including any specific third party obligations relating to, for example, licensing obligations or the donor consent which affect the use of the cell line.

The EBiSC Access and Use Agreement must be completed along with an individual Cell Line Information Pack for each line. Complete the EAUA and send to Contact@EBiSC.org for countersignature. The EAUA must be fully signed before proceeding with your order.
To receive the Certificate of Analysis, please contact us.
A batch specific Certificate of Analysis will be available to download once you receive your EBiSC iPSC line.

General#

Cell Line

hPSCreg name STBCi025-B
Alternative name(s)
SFC834-03-03
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
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STBCi084-C
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STBCi042-A
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STBCi042-B
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STBCi042-C
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STBCi085-C
(SFC866-03-05)
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GBA1
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STBCi088-B
(SFC872-03-02)
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GBA1
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STBCi088-C
(SFC872-03-03)
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GBA1
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Parkinson disease
STBCi084-B
(SFC871-03-04)
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GBA1
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Parkinson disease
UOXFi003-C
(MK088-7)
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GBA1
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Parkinson disease
UOXFi001-C
(MK071-5)
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GBA1
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Parkinson disease
UOXFi001-D
(MK071-6)
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EDi001-A-1
(AST22-C, AST23-C)
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SNCA, SNCA
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Parkinson disease
EDi001-A-2
(AST23-1KO-3, AST22-1KO-3, AST-23_SCAKO Clone 3, AST-22_SNCAKO Clone 3)
Donor's gene variants:
SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-3
(AST23_SNCAKO Clone 1, AST22-1KO-1, AST23-1KO-1, AST22_SNCAKO Clone 1)
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STBCi267-A
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STBCi007-A
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STBCi083-B
(SFC830-04-08)
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STBCi024-A
(SFC831-03-01)
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STBCi024-C
(SFC831-03-05)
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STBCi019-C
(SFC828-03-04)
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Parkinson disease
STBCi004-A
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Parkinson disease
STBCi320-A
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Parkinson disease
EDi008-B
(G51D-4, EDINi008-B, EDIi008-B, SAMEA3174606)
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SNCA, SNCA, SNCA, SNCA
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Parkinson disease
EDi001-A
(AST22, AST23, SAMEA3319992)
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SNCA, SNCA, SNCA
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Parkinson disease
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(MK002-4)
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(MK144-7)
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ESi004-A
([GD]FiPS-4F-21c)
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GBA1
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STBCi090-B
(SFC867-04-12)
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Parkinson disease
STBCi005-B
(SFC833-03-05)
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LRRK2
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Parkinson disease
STBCi005-C
(SFC833-03-14)
Donor's gene variants:
LRRK2
Donor diseases:
Parkinson disease
STBCi007-B
(SFC855-03-08)
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LRRK2
Donor diseases:
Parkinson disease
STBCi007-C
(SFC855-03-01)
Donor's gene variants:
LRRK2
Donor diseases:
Parkinson disease
STBCi258-A
(SFC090-03-07)
Donor diseases:
Parkinson disease
STBCi259-A
(SFC032-03-07)
Donor diseases:
Parkinson disease
STBCi265-A
(SFC121-03-02)
Donor diseases:
Parkinson disease
STBCi268-A
(SFC077-03-04)
Donor diseases:
Parkinson disease
STBCi279-A
(SFC063-03-01)
Donor diseases:
Parkinson disease

Provider

Depositor StemBANCC (STBC)
Distributors
EBiSC

External Databases

hPSCreg STBCi025-B
BioSamples SAMEA104493658
Cellosaurus CVCL_RB83
Wikidata Q54956406

General Information

Publications View all related publications on hPSCreg (2)
This EBiSC line can be used for:
Yes
Research use: allowed
Clinical use: no
Commercial use: no

Donor Information#

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • Parkinson disease
  • Parkinson's disease
  • paralysis agitans
Genetic variants
GBA1 (target)
GBA N370S

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA104493657

hIPSC Derivation#

General

Source cell type
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.; These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

The following are the depositor culture conditions, they do not refer to any specific batch.
Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 21 %
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
TRA 1-60
Yes

Microbiology / Virus Screening

Mycoplasma Negative

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
acceptable: C15 LOH as observed in parent fibroblast; also modest allelic imbalance C6
Passage number: 21
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)