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STBCi014-A

SFC808-03-03

iPSC line

Not-for-profit fee: £1400 per vial
Immediately available for distribution*
*Once all legal and processing details completed
A CLIP contains information about a cell line including any specific third party obligations relating to, for example, licensing obligations or the donor consent which affect the use of the cell line.

The EBiSC Access and Use Agreement must be completed along with an individual Cell Line Information Pack for each line. Complete the EAUA and send to Contact@EBiSC.org for countersignature. The EAUA must be fully signed before proceeding with your order.
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General#

Cell Line

hPSCreg name STBCi014-A
Alternative name(s)
SFC808-03-03
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
STBCi014-B
(SFC808-03-04)
Donor's gene variants:
PSEN1
Donor diseases:
Alzheimer disease
STBCi014-C
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STBCi013-A
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STBCi009-A
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PSEN1
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STBCi010-A
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PSEN1
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STBCi011-A
(SFC803-03-01)
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PSEN1
Donor diseases:
Alzheimer disease
STBCi011-B
(SFC803-03-02)
Donor's gene variants:
PSEN1
Donor diseases:
Alzheimer disease
STBCi011-C
(SFC803-03-08)
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PSEN1
Donor diseases:
Alzheimer disease
STBCi012-A
(SFC805-03-01)
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PSEN1
Donor diseases:
Alzheimer disease
STBCi012-B
(SFC805-03-02)
Donor's gene variants:
PSEN1
Donor diseases:
Alzheimer disease
STBCi012-C
(SFC805-03-03)
Donor's gene variants:
PSEN1
Donor diseases:
Alzheimer disease
STBCi013-B
(SFC807-03-04)
Donor's gene variants:
PSEN1
Donor diseases:
Alzheimer disease
STBCi009-B
(SFC801-03-02)
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PSEN1
Donor diseases:
Alzheimer disease
STBCi009-C
(SFC801-03-03)
Donor's gene variants:
PSEN1
Donor diseases:
Alzheimer disease
STBCi006-A-1
(ApoE KO)
Donor's gene variants:
APOE, APOE
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Alzheimer disease
UKBi011-A-1
(iLB-AD + ApoE KO)
Donor's gene variants:
APOE, APOE
Donor diseases:
Alzheimer disease
UKBi011-A-3
(ApoE 3/3)
Donor's gene variants:
APOE, APOE
Donor diseases:
Alzheimer disease
UKBi011-A-4
(ApoE 3/4)
Donor's gene variants:
APOE, APOE
Donor diseases:
Alzheimer disease
STBCi061-A
(SFC850-03-01)
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MAPT
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Alzheimer disease
STBCi062-A
(SFC851-03-04)
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MAPT
Donor diseases:
Alzheimer disease
STBCi015-B
(SFC809-03-03)
Donor's gene variants:
APP
Donor diseases:
Alzheimer disease
STBCi015-C
(SFC809-03-04)
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APP
Donor diseases:
Alzheimer disease
UKBi011-A-2
(ApoE 2/2)
Donor's gene variants:
APOE, APOE
Donor diseases:
Alzheimer disease
STBCi032-A
(SFC042-03-01)
Donor diseases:
Alzheimer disease
STBCi032-B
(SFC042-03-03)
Donor diseases:
Alzheimer disease
STBCi045-A
(SFC039-03-01)
Donor diseases:
Alzheimer disease
STBCi045-B
(SFC039-03-02)
Donor diseases:
Alzheimer disease
STBCi045-C
(SFC039-03-03)
Donor diseases:
Alzheimer disease
STBCi256-A
(SFC144-03-02)
Donor's gene variants:
APOE
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Alzheimer disease
STBCi264-A
(SFC142-03-01)
Donor diseases:
Alzheimer disease
STBCi015-A
(SFC809-03-01)
Donor's gene variants:
APP
Donor diseases:
Alzheimer disease
STBCi047-A
(SFC043-03-01)
Donor diseases:
Alzheimer disease
STBCi051-A
(SFC056-04-03)
Donor diseases:
Alzheimer disease
STBCi047-B
(SFC043-03-13)
Donor diseases:
Alzheimer disease
STBCi051-B
(SFC056-04-01)
Donor diseases:
Alzheimer disease

Provider

Depositor StemBANCC (STBC)
Distributors
EBiSC

External Databases

hPSCreg STBCi014-A
BioSamples SAMEA104493617
Cellosaurus CVCL_RB56
Wikidata Q54956369

General Information

This EBiSC line can be used for:
Yes
Research use: allowed
Clinical use: no
Commercial use: no

Donor Information#

General Donor Information

Sex female
Age of donor (at collection) 45-49

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • AD
  • Alzheimer dementia
  • Alzheimer disease
  • Alzheimer's dementia
  • Alzheimer's disease
  • Alzheimers dementia
  • Alzheimers disease
  • presenile and senile dementia
  • Alzheimer disease, familial
show more synonyms
Genetic variants
PSEN1 (target)
14q24.2
VCV000098013.1
PSEN1-A Intron 4 deletion

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA104493618

hIPSC Derivation#

General

Source cell type
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.; These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.
Age of donor (at collection) 45-49

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Is reprogramming vector detectable?
No
Methods used
PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

The following are the depositor culture conditions, they do not refer to any specific batch.
Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 21 %
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation#

Sterility

Inoculation for microbiological growth No Contaminants Detected
Mycoplasma Not Detected
Viability Viable post-cryopreservation

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
No abnormalities detected
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)