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STBCi012-B

SFC805-03-02

iPSC line

Not-for-profit fee: £1400 per vial
Stock not immediately available - enquire for details
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General#

Cell Line

hPSCreg name STBCi012-B
Alternative name(s)
SFC805-03-02
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
STBCi012-A
(SFC805-03-01)
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PSEN1
Donor diseases:
Alzheimer disease
STBCi012-C
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STBCi014-A
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STBCi010-A
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PSEN1
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STBCi014-B
(SFC808-03-04)
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PSEN1
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Alzheimer disease
STBCi014-C
(SFC808-03-06)
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PSEN1
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STBCi011-A
(SFC803-03-01)
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PSEN1
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STBCi011-B
(SFC803-03-02)
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PSEN1
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STBCi011-C
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PSEN1
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Alzheimer disease
STBCi013-B
(SFC807-03-04)
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PSEN1
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Alzheimer disease
STBCi009-B
(SFC801-03-02)
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PSEN1
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Alzheimer disease
STBCi009-C
(SFC801-03-03)
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PSEN1
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Alzheimer disease
STBCi006-A-1
(ApoE KO)
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APOE, APOE
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Alzheimer disease
UKBi011-A-1
(iLB-AD + ApoE KO)
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APOE, APOE
Donor diseases:
Alzheimer disease
UKBi011-A-3
(ApoE 3/3)
Donor's gene variants:
APOE, APOE
Donor diseases:
Alzheimer disease
UKBi011-A-4
(ApoE 3/4)
Donor's gene variants:
APOE, APOE
Donor diseases:
Alzheimer disease
STBCi061-A
(SFC850-03-01)
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MAPT
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Alzheimer disease
STBCi062-A
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MAPT
Donor diseases:
Alzheimer disease
STBCi015-B
(SFC809-03-03)
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APP
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Alzheimer disease
STBCi015-C
(SFC809-03-04)
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APP
Donor diseases:
Alzheimer disease
UKBi011-A-2
(ApoE 2/2)
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APOE, APOE
Donor diseases:
Alzheimer disease
STBCi032-A
(SFC042-03-01)
Donor diseases:
Alzheimer disease
STBCi032-B
(SFC042-03-03)
Donor diseases:
Alzheimer disease
STBCi045-A
(SFC039-03-01)
Donor diseases:
Alzheimer disease
STBCi045-B
(SFC039-03-02)
Donor diseases:
Alzheimer disease
STBCi045-C
(SFC039-03-03)
Donor diseases:
Alzheimer disease
STBCi256-A
(SFC144-03-02)
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APOE
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Alzheimer disease
STBCi264-A
(SFC142-03-01)
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STBCi015-A
(SFC809-03-01)
Donor's gene variants:
APP
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Alzheimer disease
STBCi047-A
(SFC043-03-01)
Donor diseases:
Alzheimer disease
STBCi051-A
(SFC056-04-03)
Donor diseases:
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STBCi047-B
(SFC043-03-13)
Donor diseases:
Alzheimer disease
STBCi051-B
(SFC056-04-01)
Donor diseases:
Alzheimer disease

Provider

Depositor StemBANCC (STBC)
Distributors
EBiSC

External Databases

hPSCreg STBCi012-B
BioSamples SAMEA104493612
Cellosaurus CVCL_RB52
Wikidata Q54956363

General Information

This EBiSC line can be used for:
Yes
Research use: allowed
Clinical use: no
Commercial use: no

Donor Information#

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • AD
  • Alzheimer dementia
  • Alzheimer disease
  • Alzheimer's dementia
  • Alzheimer's disease
  • Alzheimers dementia
  • Alzheimers disease
  • presenile and senile dementia
  • Alzheimer disease, familial
show more synonyms
Genetic variants
PSEN1 (target)
14q24.2
NP_000012.1:p.Met139Val
VCV000018128.12
PSEN1-A M139VA; ALZFORUM: https://www.alzforum.org/mutations/psen1-m139v

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA104493611

hIPSC Derivation#

General

Source cell type
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.; These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

The following are the depositor culture conditions, they do not refer to any specific batch.
Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 21 %
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
TRA 1-60
Yes

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
Pass: minor allelic imbalance Chr6 also present in parent fibroblasts
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)