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STBCi019-B

SFC828-03-09

iPSC line

Not currently available
The cell line has been recalled.

General#

Cell Line

hPSCreg name STBCi019-B
Alternative name(s)
SFC828-03-09
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
STBCi019-C
(SFC828-03-04)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
STBCi019-A
(SFC828-03-06)
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SNCA
Donor diseases:
Parkinson disease
STBCi024-A
(SFC831-03-01)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
STBCi024-C
(SFC831-03-05)
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SNCA
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Parkinson disease
STBCi023-B
(SFC829-03-04)
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SNCA
Donor diseases:
Parkinson disease
STBCi083-B
(SFC830-04-08)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
EDi001-A-1
(AST22-C, AST23-C)
Donor's gene variants:
SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-2
(AST23-1KO-3, AST22-1KO-3, AST-23_SCAKO Clone 3, AST-22_SNCAKO Clone 3)
Donor's gene variants:
SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A-3
(AST23_SNCAKO Clone 1, AST22-1KO-1, AST23-1KO-1, AST22_SNCAKO Clone 1)
Donor's gene variants:
SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
STBCi024-B
(SFC831-03-03)
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SNCA
Donor diseases:
Parkinson disease
EDi008-B
(G51D-4, EDINi008-B, EDIi008-B, SAMEA3174606)
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SNCA, SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
EDi001-A
(AST22, AST23, SAMEA3319992)
Donor's gene variants:
SNCA, SNCA, SNCA
Donor diseases:
Parkinson disease
STBCi023-A
(SFC829-03-02)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
STBCi023-C
(SFC829-03-06)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
STBCi083-A
(SFC830-04-09)
Donor's gene variants:
SNCA
Donor diseases:
Parkinson disease
STBCi004-B-1
(SFC832-03-06 LRRK2WT/WT C47)
Donor's gene variants:
LRRK2
Donor diseases:
Parkinson disease
STBCi084-A
(SFC871-03-12)
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GBA1
Donor diseases:
Parkinson disease
STBCi084-C
(SFC871-03-09)
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GBA1
Donor diseases:
Parkinson disease
STBCi004-A
(SFC832-03-19)
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LRRK2
Donor diseases:
Parkinson disease
STBCi025-C
(SFC834-03-10)
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GBA1
Donor diseases:
Parkinson disease
STBCi085-A
(SFC866-03-06)
Donor's gene variants:
GBA1
Donor diseases:
Parkinson disease
STBCi088-A
(SFC872-03-05)
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GBA1
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Parkinson disease
STBCi267-A
(SFC027-03-02)
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Parkinson disease
STBCi005-A
(SFC833-03-01)
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LRRK2
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Parkinson disease
STBCi007-A
(SFC855-03-06)
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LRRK2
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Parkinson disease
UOXFi001-B
(MK071-3)
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GBA1
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Parkinson disease
STBCi320-A
(SFC031-03-03)
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Parkinson disease
STBCi266-A
(SFC072-03-06)
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Parkinson disease
STBCi278-A
(SFC245-03-08)
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Parkinson disease
STBCi280-A
(SFC066-03-01)
Donor diseases:
Parkinson disease
STBCi283-A
(SFC073-03-08)
Donor diseases:
Parkinson disease
STBCi292-A
(SFC139-03-06)
Donor diseases:
Parkinson disease
STBCi293-A
(SFC843-03-09)
Donor diseases:
Parkinson disease
STBCi297-A
(SFC061-03-07)
Donor diseases:
Parkinson disease
STBCi084-B
(SFC871-03-04)
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GBA1
Donor diseases:
Parkinson disease
STBCi004-B
(SFC832-03-06)
Donor's gene variants:
LRRK2
Donor diseases:
Parkinson disease
STBCi004-C
(SFC832-03-07)
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LRRK2
Donor diseases:
Parkinson disease
UOXFi002-B
(MK082-30)
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GBA1
Donor diseases:
Parkinson disease
STBCi025-B
(SFC834-03-03)
Donor's gene variants:
GBA1
Donor diseases:
Parkinson disease
STBCi040-A
(SFC029-03-04)
Donor diseases:
Parkinson disease
STBCi040-B
(SFC029-03-08)
Donor diseases:
Parkinson disease
STBCi041-A
(SFC081-03-02)
Donor diseases:
Parkinson disease
STBCi042-A
(SFC848-03-02)
Donor's gene variants:
GBA1
Donor diseases:
Parkinson disease
STBCi042-B
(SFC848-03-04)
Donor's gene variants:
GBA1
Donor diseases:
Parkinson disease
STBCi042-C
(SFC848-03-06)
Donor's gene variants:
GBA1
Donor diseases:
Parkinson disease
STBCi043-A
(SFC120-03-03)
Donor diseases:
Parkinson disease
STBCi043-B
(SFC120-03-04)
Donor diseases:
Parkinson disease
STBCi040-C
(SFC029-03-01)
Donor diseases:
Parkinson disease
STBCi041-B
(SFC081-03-04)
Donor diseases:
Parkinson disease
STBCi043-C
(SFC120-03-02)
Donor diseases:
Parkinson disease

Provider

Depositor StemBANCC (STBC)
Distributors
EBiSC

External Databases

hPSCreg STBCi019-B
BioSamples SAMEA104493639
Cellosaurus CVCL_RB72
Wikidata Q54956389

General Information

This EBiSC line can be used for:
Yes
Research use: allowed
Clinical use: no
Commercial use: no

Donor Information#

General Donor Information

Sex female
Age of donor (at collection) 50-54

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • Parkinson disease
  • Parkinson's disease
  • paralysis agitans
Genetic variants
SNCA (target)
4q22.1
SNCA A53T

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA104493638

hIPSC Derivation#

General

Source cell type
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.; These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.
Age of donor (at collection) 50-54

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

The following are the depositor culture conditions, they do not refer to any specific batch.
Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 21 %
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
NANOG
Yes
TRA 1-60
Yes

Microbiology / Virus Screening

Mycoplasma Negative

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
No abnormalities detected
Passage number: 18
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)