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UNEWi011-A

UNEW011Ai

iPSC line

Not-for-profit fee: £1400 per vial
No longer available
The cell line was withdrawn.

General#

Cell Line
hPSCreg name UNEWi011-A
Alternative name(s)
UNEW011Ai
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.

Provider
Depositor University of Newcastle (UNEW)
Distributors

External Databases
hPSCreg UNEWi011-A
BioSamples SAMEA2629624
Cellosaurus CVCL_VF32
Wikidata Q54991156

General Information
This EBiSC line can be used for:
Yes
Research use: allowed
Clinical use: no
Commercial use: no

Donor Information#

General Donor Information
Sex male
Age of donor (at collection) 1-4
Ethnicity Caucasian

Phenotype and Disease related information (Donor)
Diseases A disease was diagnosed.
Cernunnos-XLF deficiency
XLF Deficiency
The donor is affected.
Stage
Severe
Synonyms
  • Cernunnos XLFD
  • NHEJ1 deficiency
  • Cernunnos deficiency
  • Combined immunodeficiency-microcephaly-growth retardation-sensitivity to ionizing radiation syndrome
show more synonyms
Non-disease associated phenotypes
  • primary immunodeficiency, severe growth retardation, bird-like face, recurrent perianal abscess, pancytopenia, and polydactyly
Family history NO

External Databases (Donor)
BioSamples SAMEA2629494

hIPSC Derivation#

General
Source cell type
Fibroblast of dermis
Any skin fibroblast that is part of some dermis.
Source cell origin
Zone of skin
Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis.
Synonyms
  • portion of skin
  • region of skin
  • skin
  • skin region
  • skin zone
show more synonyms
Age of donor (at collection) 1-4

Reprogramming method
Vector type Integrating
Vector Virus (Lentivirus)
Genes
Is the used vector excisable?
Unknown
Absence of reprogramming vector(s)?
Unknown
Reprogramming vectors silenced?

Vector free reprogramming

Other
Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

The following are the depositor culture conditions, they do not refer to any specific batch.
Surface coating Matrigel/Geltrex
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 95 %
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation#

No characterisation data could be found.

Genotyping#

Karyotyping (Cell Line)
Has the cell line karyotype been analysed?
Unknown

Other Genotyping (Cell Line)